Discover detailed scientific and clinical evidence for each ingredient through the references provided here.

1. Bush JR, Han J, Deehan EC, Harding SV, Maiya M, Baisley J, Schibli D, Goodlett DR. Resistant potato starch supplementation reduces serum histamine levels in healthy adults with links to attenuated intestinal permeability. Journal of Functional Foods. 2023 Sep 1;108:105740. Read Paper

2. Steels E, Erhardt R, Harnett JE, Vigar V, Steadman KJ. Efficacy of a prebiotic formulation for treatment of functional constipation and associated gastrointestinal symptoms in adults: A randomised controlled trial. Advances in Integrative Medicine. 2023 May 1;10(2):43-50. Read Paper

3. Pino JL, Mujica V, Arredondo M. Effect of dietary supplementation with oat β-glucan for 3 months in subjects with type 2 diabetes: A randomized, double-blind, controlled clinical trial. Journal of Functional Foods. 2021 Feb 1;77:104311. Read Paper

4. Shimizu C, Kihara M, Aoe S, Araki S, Ito K, Hayashi K, Watari J, Sakata Y, Ikegami S. Effect of high β-glucan barley on serum cholesterol concentrations and visceral fat area in Japanese men—a randomized, double-blinded, placebo-controlled trial. Plant foods for human nutrition. 2008 Mar;63:21-5. Read Paper

5. Kollaritsch H, Kremsner PE, Wiedermann GE, Scheiner OT. Prevention of traveller’s diarrhea: comparison of different non-antibiotic preparations. Travel Med Int. 1989 May 26;6(6):9-17. Read Paper

6. Sanborn V, Azcarate-Peril MA, Updegraff J, Manderino L, Gunstad J. Randomized clinical trial examining the impact of Lactobacillus rhamnosus GG probiotic supplementation on cognitive functioning in middle-aged and older adults. Neuropsychiatric disease and treatment. 2020 Nov 13:2765-77. Read Paper

7. Patterson E, Griffin SM, Ibarra A, Ellsiepen E, Hellhammer J. Lacticaseibacillus paracasei Lpc-37® improves psychological and physiological markers of stress and anxiety in healthy adults: a randomized, double-blind, placebo-controlled and parallel clinical trial (the Sisu study). Neurobiology of stress. 2020 Nov 1;13:100277. Read Paper

8. Harris LA, Cash BD, Moftah K, Franklin H. An open-label, multicenter study to assess the efficacy and safety of a novel probiotic blend in patients with functional gastrointestinal symptoms. Journal of Clinical Gastroenterology. 2022 May 1;56(5):444-51. Read Paper

9. Majeed M, Nagabhushanam K, Mundkur L, Paulose S, Divakar H, Rao S, Arumugam S. Probiotic modulation of gut microbiota by Bacillus coagulans MTCC 5856 in healthy subjects: A randomized, double-blind, placebo-control study. Medicine. 2023 May 19;102(20):e33751. Read Paper

10. Sugimura T, Takahashi H, Jounai K, Ohshio K, Kanayama M, Tazumi K, Tanihata Y, Miura Y, Fujiwara D, Yamamoto N. Effects of oral intake of plasmacytoid dendritic cells-stimulative lactic acid bacterial strain on pathogenesis of influenza-like illness and immunological response to influenza virus. British Journal of Nutrition. 2015 Sep;114(5):727-33. Read Paper

11. Blatchford P, Stoklosinski H, Eady S, Wallace A, Butts C, Gearry R, Gibson G, Ansell J. Consumption of kiwifruit capsules increases Faecalibacterium prausnitzii abundance in functionally constipated individuals: a randomised controlled human trial. Journal of nutritional science. 2017 Jan;6:e52. Read Paper

12. Graham E, McKeen S, Lewis ED, Evans M, Li Z, Henning SM, Jopson N, Gu J, Rosendale D. Actazin® green kiwifruit powder consumption at 600 mg per day for 28 days improves stool form and relieves occasional constipation in healthy individuals: A randomized controlled trial. Bioactive Carbohydrates and Dietary Fibre. 2024 Dec 1;32:100436. Read Paper

13. Goodarzi R, Jafarirad S, Mohammadtaghvaei N, Dastoorpoor M, Alavinejad P. The effect of pomegranate extract on anthropometric indices, serum lipids, glycemic indicators, and blood pressure in patients with nonalcoholic fatty liver disease: A randomized double‐blind clinical trial. Phytotherapy Research. 2021 Oct;35(10):5871-82. Read Paper

14. Tiralongo E, Wee SS, Lea RA. Elderberry supplementation reduces cold duration and symptoms in air-travellers: A randomized, double-blind placebo-controlled clinical trial. Nutrients. 2016 Apr;8(4):182. Read Paper

15. Kawamura A, Hashimoto S, Suzuki M, Ueno H, Sugita M. Oligomerized polyphenols in lychee fruit extract supplements may improve high-intensity exercise performance in male athletes: a pilot study. Physical Activity and Nutrition. 2021 Sep;25(3):8. Read Paper

16. Peterson CT, Vaughn AR, Sharma V, Chopra D, Mills PJ, Peterson SN, Sivamani RK. Effects of turmeric and curcumin dietary supplementation on human gut microbiota: A double-blind, randomized, placebo-controlled pilot study. Read Paper